Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p2 | (1) | ICCBH2015

The assessment of bone regulatory pathways in children with malignant bone tumors

Ambroszkiewicz Jadwiga , Gajewska Joanna , Chelchowska Magdalena , Rogowska Elzbieta , Rychlowska-Pruszynska Magdalena

Objectives: As the receptor activator of the nuclear factor κB (RANK)/receptor activator of the nuclear factor κB ligand (RANKL)/osteoprotegerin (OPG) cytokine system is essential for osteoclastogenesis and Wnt signaling pathway for osteoblastogenesis, we decided to assess these two main bone regulatory pathways in patients with malignant bone tumors on the completion of anticancer therapy.Methods: The study included 35 patients (median age 15....